Atypical lipomatous tumors of the face: a controversial issue
β Scribed by Georges Zaytoun; Omar Sabra; Marwan Youssef; Futoun Slim; Ghazi Zaatari
- Book ID
- 106083003
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 363 KB
- Volume
- 263
- Category
- Article
- ISSN
- 0302-9530
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## Abstract Ring chromosomes are cytogenetic hallmarks of genomic amplification in several bone and soft tissue tumors, in particular atypical lipomatous tumors (ALT). In ALT, the ring chromosomes invariably contain amplified material from the central part of the long arm of chromosome 12, mainly 1
Ordinary lipomas are cytogenetically characterized by a variety of balanced rearrangements involving chromosome segment I2q 13-15, and atypical lipomatous tumors (ALT) by supernumerary ring chromosomes or giant markers known to contain amplified I2q sequences. In a series of 228 cytogenetically anal