In a series of 374 families with Down syndrome progeny, structural chromosome rearrangements were detected in the parents of six children with regular trisomy. The aberrations were reciprocal translocations and inversions. In all three informative families, the parent who transmitted the extra chrom
โฆ LIBER โฆ
Atypical Down syndrome and partial trisomy 21
โ Scribed by E. C. Jenkins; C. J. Duncan; C. E. Wright; F. M. Giordano; L. Wilbur; K. Wisniewski; S. L. Sklower; J. H. French; C. Jones; W. T. Brown
- Book ID
- 119839501
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 600 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0009-9163
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The lymphocyte chromosomes of trisomy 21 Down syndrome patients and their parents in a random series of 374 families were analyzed, the objective being the identification of parental mosaicism. The numbers of parents in whom at least two trisomy 21 cells were detected were seven mothers and three fa
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