A retinal pigment epithelial (RPE) cell line (K-1034) was examined for its susceptibility to human herpesvirus 6 variant A (HHV-6A). Exposure of K-1034 cells to HHV-6A induced the formation of multinucleated giant cells, which was suppressed by an inhibitor of viral DNA synthesis. In the giant cells
Atypical clinical features of a human herpesvirus-6 infection in a neonate
β Scribed by Tetsushi Yoshikawa; Kenji Suzuki; Kayoko Umemura; Shiho Akimoto; Fumi Miyake; Chie Usui; Ayano Fujita; Sadao Suga; Yoshizo Asano
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 86 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0146-6615
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β¦ Synopsis
Abstract
A case of neonatal human herpesvirus 6 (HHVβ6) B infection is presented. Although HHVβ6 B was isolated from peripheral blood at the onset of the illness, a significant increase in viral antibody titers was not observed. The patient had a slight fever with generalized maculopapular skin rash and an increased number of atypical lymphocytes, which is quite different from the typical clinical features of exanthem subitum. J. Med. Virol. 74:463β466, 2004. Β© 2004 WileyβLiss, Inc.
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