𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Attenuation of p53 expression and Bax down-regulation during phorbol ester mediated inhibition of apoptosis

✍ Scribed by Udo K. Meßmer; Bernhard Brüne

Book ID
110002945
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
574 KB
Volume
121
Category
Article
ISSN
0007-1188

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Topoisomerase-I inhibitors for human mal
Topoisomerase-I inhibitors for human malignant glioma: Differential modulation of p53, p21, bax and bcl-2 expression and of CD95-mediated apoptosis by camptothecin and β-lapachone
✍ Michael Weller; Stephan Winter; Christine Schmidt; Peter Esser; Adriano Fontana; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 390 KB 👁 1 views

␤-lapachone and camptothecin are structurally unrelated agents thought to inhibit topoisomerase-I activity through distinct mechanisms. We find that ␤-lapachone is much more potent than camptothecin in inducing acute cytotoxic effects on human malignant glioma cells. Acute cytotoxicity induced by bo