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Attenuation of migration of vascular smooth muscle cells by overexpression of plasminogen activator inhibitor type 1

โœ Scribed by Michael G. Hayes; Burton E. Sobel; Douglas J. Taatjes; Mercedes Rincon; David J. Schneider

Book ID
119544443
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
145 KB
Volume
39
Category
Article
ISSN
1558-3597

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## Abstract Increased expression of plasminogen activator inhibitor type 1 (PAIโ€1) is associated with decreased apoptosis of neoplastic cells. We sought to determine whether PAIโ€1 alters apoptosis in vascular smooth muscle cells (VSMC) and, if so, by what mechanisms. A twofold increase in the expre