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Attenuation of ethanol intoxication by alpha-2 adrenoceptor antagonists

✍ Scribed by Richard G. Lister; Michael J. Durcan; David J. Nutt; Markku Linnoila


Book ID
118343937
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
425 KB
Volume
44
Category
Article
ISSN
0024-3205

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Modification of ethanol intoxication by
✍ N. G. Bacopoulos; I. Bize; J. Levine; L. S. Orden πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 660 KB

The effects of ethanol on locomotor activity and rotarod performance were measured in the rat. Apomorphine (4 mg/kg s. c.) antagonized and pimozide (0.75 -1.50 mg/kg s.c.) enhanced the effects of a 2 g/kg dose of ethanol on rotarod performance. No such interaction was seen with pentobarbital, 25 mg/