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Interactions of alpha2-adrenoceptor antagonists with medetomidine and with ethanol in a holeboard test

✍ Scribed by M.J. Durcan; R.G. Lister; M. Linnoila


Book ID
118956116
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
755 KB
Volume
28
Category
Article
ISSN
0028-3908

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Behavioral effects of alpha2adrenoceptor
✍ Michael J. Durcan; Richard G. Lister; Markku Linnoila πŸ“‚ Article πŸ“… 1989 πŸ› Springer 🌐 English βš– 494 KB

The behavioral effects of two highly selective al-pha2-adrenoceptor antagonists, atipamezole and idazoxan, were investigated in mice using the plusmaze test of anxiety and the holeboard test of directed exploration and locomotor activity. No anxiogenic effect, as assessed by the tendency to enter th