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Attenuation of ethanol-induced cytotoxicity by calcium channel blockers in isolated rat hepatocytes

✍ Scribed by E. Cenarruzabeitia; A. Andía; L. Sainz; A. Cobreros

Book ID
119180189
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
148 KB
Volume
31
Category
Article
ISSN
1043-6618

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The effect on acetaminophen-induced cytotoxicity of three calcium channel blocking agents-diltiazem, verapamil and gallopamil-was studied in primary cultures of rat hepatocytes and compared with the chelating agent EGTA. Using the measurement of cytosolic lactate dehydrogenase (LDH) as an index of c