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Attenuated neurotoxicity of the transactivation-defective HIV-1 Tat protein in hippocampal cell cultures

✍ Scribed by Michael Y. Aksenov; Marina V. Aksenova; Charles F. Mactutus; Rosemarie M. Booze


Book ID
116459582
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
494 KB
Volume
219
Category
Article
ISSN
0014-4886

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## Abstract The human immunodeficiency virus type 1 (HIV‐1) proteins, gp120 and Tat, are believed to play a role in mediating central nervous system (CNS) pathology in HIV‐1 infected patients. Using design‐based stereology, we examined the role of neonatal intrahippocampal injections of gp120 and T