𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Atraumatic quantitation of cerebral perfusion in cats by 19f magnetic resonance imaging

✍ Scribed by Craig A. Branch; James R. Ewing; J. A. Helpern; R. J. Ordidge; Shazad Butt; K. M. A. Welch

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
1004 KB
Volume
28
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

We have noninvasively produced low‐resolution, quantitative nuclear magnetic resonance images of cerebral blood flow in 2‐ml voxels in eight cats. Typical signal‐to‐noise of 4 to 1 was obtained in cerebral voxels in 16.5‐s epochs. Mean flow during normocapnia (p~a~CO~2~ = 39 ± 4 mm Hg) and hypercapnia (p~a~CO~2~ = 62 ± 4 mm Hg) was 53 ± 20 ml/100 gmin and 140 ± 36 ml/100 g‐min, respectively. Fast flows in normocapnia were 94 ± 13 and 182 ± 39 ml/100 g‐min in hypercapnia. These results suggest that an atraumatic quantitative imaging assessment of cerebral perfusion may be possible in humans using these techniques.© 1992 Academic Press,Inc.

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