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Atractylodes macrocephala polysaccharides induces mitochondrial-mediated apoptosis in glioma C6 cells

✍ Scribed by Li, Xuejun; Liu, Fei; Li, Zhao; Ye, Ningrong; Huang, Chunhai; Yuan, Xianrui

Book ID
122267435
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
620 KB
Volume
66
Category
Article
ISSN
0141-8130

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## Abstract Nerve growth factor (NGF) binds to the TrkA tyrosine kinase and the p75 neurotrophin receptors. Depending upon which receptor is activated, NGF can induce differentiation or apoptosis. C6‐2B glioma cells express the p75 receptor, but NGF decreases their growth only when TrkA is introduc