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P2B66 - Tiazofurin induces apoptosis in C6 rat glioma cells

✍ Scribed by M. Vračcar; V. Piperski; S. Jovanović; M. Jokanovic; Lj. Rakić

Book ID
119540176
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
137 KB
Volume
95
Category
Article
ISSN
0378-4274

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## Abstract Nerve growth factor (NGF) binds to the TrkA tyrosine kinase and the p75 neurotrophin receptors. Depending upon which receptor is activated, NGF can induce differentiation or apoptosis. C6‐2B glioma cells express the p75 receptor, but NGF decreases their growth only when TrkA is introduc