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ATPase-dependent quality control of DNA replication origin licensing

โœ Scribed by Frigola, Jordi; Remus, Dirk; Mehanna, Amina; Diffley, John F. X.

Book ID
120046377
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
648 KB
Volume
495
Category
Article
ISSN
0028-0836

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โœ Hideo Nishitani; Zoi Lygerou ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 223 KB

To maintain genome integrity in eukaryotes, DNA must be duplicated precisely once before cell division occurs. A process called replication licensing ensures that chromosomes are replicated only once per cell cycle. Its control has been uncovered by the discovery of the CDKs (cyclin dependent kinase