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ATP induced microglial cell migration through non-transcriptional activation of matrix metalloproteinase-9

✍ Scribed by Min Sik Choi; Kyu Suk Cho; Sun Mi Shin; Hyun Myung Ko; Kyung Ja Kwon; Chan Young Shin; Kwang Ho Ko

Book ID
107642194
Publisher
Springer
Year
2010
Tongue
English
Weight
417 KB
Volume
33
Category
Article
ISSN
0253-6269

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## Abstract Many reports have shown that matrix metalloproteinase (MMP)‐9 plays an important role in brain inflammation and diseases. In our previous study, bradykinin (BK) has been shown to induce proMMP‐9 expression via MAPKs and NF‐κB in rat brain astrocytes (RBA‐1). However, the molecular mecha