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Atherosclerosis in the Renaissance elite: Ferdinand I King of Naples (1431–1494)

✍ Scribed by Raffaele Gaeta, Valentina Giuffra, Gino Fornaciari

Book ID
120906608
Publisher
Springer
Year
2013
Tongue
English
Weight
236 KB
Volume
462
Category
Article
ISSN
1432-2307

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✍ Gino Fornaciari; Antonio Marchetti; Silvia Pellegrini; Rosalba Ciranni 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 404 KB

The autopsy of the mummy of Ferrante I of Aragon, King of Naples (1431 -1494) revealed an adenocarcinoma extensively infiltrating the muscles of the small pelvis. A molecular study of neoplastic tissue observed a typical mutation of the K-ras gene codon 12: the normal sequence GGT (glycine) was alte