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Ataxia telangiectasia gene mutations and chronic lymphocytic leukaemia

โœ Scribed by MR Yuille; A Marossy; D Catovsky; RS Houlston


Book ID
117295445
Publisher
The Lancet
Year
1999
Tongue
English
Weight
70 KB
Volume
353
Category
Article
ISSN
0140-6736

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Ataxia telangiectasia (A-T) is an autosomal recessive disorder in which patients show an unusual predisposition to malignant disease, including T-cell chronic lymphocytic leukaemia. We report here the steady growth over 5 years of a complex, cytogenetically abnormal clone of T lymphocytes in an A-T

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