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A–T Base Pairs are More Stable Than G–C Base Pairs in a Hydrated Ionic Liquid

✍ Scribed by Dr. Hisae Tateishi-Karimata; Prof. Dr. Naoki Sugimoto


Book ID
102729196
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
629 KB
Volume
51
Category
Article
ISSN
0044-8249

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DNA sequences d-TGAGGAAAGAAGGT (a 14-mer) and d-CTCCTTTCTTCC (a 12-mer) are complementary in parallel orientation forming either Donohue (reverse Watson-Crick) base pairing at neutral pH or Hoogsteen base pairing at slightly acidic pH. The structure of the complex formed by dissolving the two strand