Two-Stage sampling designs for gene asso
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Duncan Thomas; Rongrong Xie; Mulugeta Gebregziabher
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Article
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2004
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John Wiley and Sons
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English
β 211 KB
π 2 views
## Abstract We consider twoβstage caseβcontrol designs for testing associations between single nucleotide polymorphisms (SNPs) and disease, in which a subsample of subjects is used to select a panel of βtaggingβ SNPs that will be considered in the main study. We propose a pseudolikelihood [Pepe and