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Asymptotic expansions in enzyme reactions with high enzyme concentrations

โœ Scribed by Alberto Maria Bersani; Guido Dell'Acqua

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
540 KB
Volume
34
Category
Article
ISSN
0170-4214

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โœฆ Synopsis

Communicated by Jacek Banasiak

In this paper, we find a new asymptotic expansion valid in enzymatic reactions, where the total amount of enzyme exceeds greatly the total amount of substrate. In such a case, it is well known that the Michaelis-Menten approximation is no longer valid; therefore our asymptotic expansion, which improves known results, is a new tool to approximate in a closed form the concentrations of the reactants in the presence of an enzyme excess.

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