✦ LIBER ✦

Asymmetric total synthesis of (+)-desoxoprosophylline

✍ Scribed by Cui-Fen Yang; Yi-Ming Xu; Li-Xin Liao; Wei-Shan Zhou

Book ID: 104260279
Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 124 KB
Volume: 39
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)02129-7

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✦ Synopsis

Asymmetric total synthesis of (+)-desoxoprosophylline 2 from the ~t-furfuryl amine derivative 1 was accomplished via ten steps in an overall yield of 4%. The oxidation of 1 to dihydropyridone 3 was used as the key step.

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