𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Asymmetric synthesis. XXXIII. Diastereoselective alkylation of N,N-substituted amides

✍ Scribed by Laurent Micouin; Vincent Schanen; Claude Riche; Angèle Chiaroni; Jean-Charles Quirion; Henri-Philippe Husson


Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
286 KB
Volume
35
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Asymmetric synthesis of ibuprofen via di
✍ Wolfgang Oppolzer; Stephane Rosset; Jef De Brabander 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 122 KB

A very short, 4 step synthesis of 2-(4-isobutylphenyl)propionic acid (ibuprofen) was achieved in 57% overall yield, using a highly diastereoselective alkylation of the chiral enolate derived from N-(4-isobutylphenyl)acetyl bornanesultam as a key step.