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Asymmetric Synthesis of α-Amino Carbonyl Derivatives Using Lithium (R)-N-Benzyl-N-α-methylbenzylamide.

✍ Scribed by Stephen G. Davies; Simon W. Epstein; A. Christopher Garner; Osamu Ichihara; Andrew D. Smith


Publisher
John Wiley and Sons
Year
2003
Weight
247 KB
Volume
34
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Conjugate Addition
✍ Scott A. Bentley; Stephen G. Davies; James A. Lee; Paul M. Roberts; James E. Tho 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 32 KB

## Abstract It is found that addition of lithium N‐phenyl‐N‐(α‐methylbenzyl)amide to various α,β‐unsaturated methoxyphenyl esters provides β‐amino esters with excellent diastereoselectivity.