Asymmetric synthesis of α-amino acids: Comparison of enolate vs. cation functionalization of N-BOC-5, 6-diphenyl-2,3,5,6-tetrahydro-4h-1,4-oxazin-2-ones
✍ Scribed by Robert M. Williams; Myeong-Nyeo Im
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 255 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
## 5S)-2.3~,6-Tetrahydro-5-alkyl-N-(tert-butylo~carbonyl)-4~~-1 .I-oxarine-2-ones. which are readily prepared from optically pure 2-amino alcohols a&late selectively at the C-3 position to give (3S, SS)-dialkyl-2.35,6-tetrahydro-S-alkyl-N-(tertbutyloxycarbonyl)-4H-1.4-oxarine-2-ones in good yield. T
## Abstract via acid‐catalyzed acylation of 2‐amino‐tetrahydrochromene‐3‐carboxylates (I)
I211 Genbve 4 (5. V .86) ~ Comparative results on the reduction of 4,6,7,8-tetrahydro-7,7-dimethyl-2H-1 -benzopyran-2,5(3H)-diones 1 are reported. Hydride reduction (LiAIH, in EtzO or NaBH, in i-PrOH) affords 2,3,4,6,7,8-hexahydro-5H-l-benzopyran-5-ones 5 in 30-60 % isolated yield. Photochemical red