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Asymmetric Synthesis of Trifluoromethylated Amines via Catalytic Enantioselective Isomerization of Imines

โœ Scribed by Wu, Yongwei; Deng, Li


Book ID
115445492
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
372 KB
Volume
134
Category
Article
ISSN
0002-7863

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Catalytic enantioselective synthesis of
โœ Graham B. Jones; Robert S. Huber; Brant J. Chapman ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 874 KB

Catalytic enantioselective syntheses of the macrolides (R)-(-) phoracantholide and (R)-(+) lasiodiplodin have been achieved. Stereochemistry was introduced in using an arene chromium tricarbonyl derived catalyst, which mediated the enantioselective addition of dimethyl zinc to a functionalized aldeh