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Asymmetric Synthesis of Tetrahydroquinolines with Quaternary Stereocenters through the Povarov Reaction

✍ Scribed by Mingsheng Xie; Prof. Dr. Xiaohua Liu; Yin Zhu; Xiaohu Zhao; Yong Xia; Dr. Lili Lin; Prof. Dr. Xiaoming Feng


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
401 KB
Volume
17
Category
Article
ISSN
0947-6539

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it should have been pointed out that the first 2-bromo-keto ester addition to cinnamaldehyde catalyzed by diphenylprolinol derivatives was reported by Córdova [16] and Wang. [17] They obtained the desired quaternary cyclopropanes in excellent yields and enantioselectivities albeit in moderate dr. Th