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Construction of CS Bonds with a Quaternary Stereocenter through a Formal Michael Reaction: Asymmetric Synthesis of Tertiary Thiols

✍ Scribed by Claudio Palomo; Mikel Oiarbide; Flavia Dias; Rosa López; Anthony Linden


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
116 KB
Volume
116
Category
Article
ISSN
0044-8249

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Chromans form the core of numerous natural products and synthetic analogues displaying a broad and interesting range of biological activities. [1] In particular, the chiral chroman skeleton plays an important role in various therapeutic areas. [1d] For example, (À)-siccanin, isolated from the cultur