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Asymmetric synthesis of seven-carbon segments of the phorboxazoles and (−)-discodermolide: Complementary route from racemic trans-2,4-dimethyl-8-oxabicyclo[3.2.1]oct-6-en-3-one

✍ Scribed by Andrea M Misske; H.M.R Hoffmann


Book ID
108379299
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
688 KB
Volume
55
Category
Article
ISSN
0040-4020

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Complete assignment of 1H and 13C NMR da
✍ Angel M. Montaña; Pedro M. Grima; Francisca García 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 66 KB 👁 2 views

The total assignment of the 1 H and 13 C NMR spectra of 24 cis-endo and 15 cis-exo diastereoisomers of C-1-substituted 2,4-dimethyl-8-oxabicyclo[3.2.1]oct-6-en-3-one derivatives was deduced from the concerted application of DEPT, COSY, HETCOR, HMBC, HMQC and PS-NOESY experiments. The relative stereo