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Asymmetric synthesis of nearly optically pure atrolactic acid methyl ether

โœ Scribed by Eliel, Ernest L.; Frazee, William J.


Book ID
118033854
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
282 KB
Volume
44
Category
Article
ISSN
0022-3263

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Asymmetric synthesis of unusual amino ac
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All the four individual isomers of R-methylphenylalanine have been synthesized in very high optical purities by utilizing in part the chiral imide enolate bromination methodology of Evans and co-workers. Substitution of the diastereotopic X-hydrogens of many a-amino acids provides inprinciple, an a