Both enantiomers of kainic acid have been synthesized from enantioenriched planar chiral cyclic amide 2a. The C3 and C4 stereocenters in the pyrrolidine ring were constructed by transannular Cope rearrangement of 2a, and the carboxyl group at the C2 position was introduced through lithiation followe
✦ LIBER ✦
Asymmetric Synthesis of (+)-Isofebrifugine and (−)-Sedacryptine from a Common Chiral Nonracemic Building Block
✍ Scribed by Wee, Andrew G. H.; Fan, Gao-Jun
- Book ID
- 121424360
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 126 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1523-7060
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