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Asymmetric Synthesis of Intermediates for Otamixaban and Premafloxacin by the Chiral Ligand-Controlled Asymmetric Conjugate Addition of a Lithium Amide

✍ Scribed by Sakai, Takeo; Kawamoto, Yoshito; Tomioka, Kiyoshi


Book ID
127235932
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
111 KB
Volume
71
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Conjugate Addition
✍ Scott A. Bentley; Stephen G. Davies; James A. Lee; Paul M. Roberts; James E. Tho πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons βš– 32 KB πŸ‘ 1 views

## Abstract It is found that addition of lithium N‐phenyl‐N‐(α‐methylbenzyl)amide to various Ξ±,β‐unsaturated methoxyphenyl esters provides β‐amino esters with excellent diastereoselectivity.