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Asymmetric Synthesis of cis-4-Aminobenzopyran Derivatives Catalyzed by N,N′-Dioxide–Sc(OTf)3 Complexes

✍ Scribed by Yulong Zhang; Shunxi Dong; Prof. Dr. Xiaohua Liu; Mingsheng Xie; Yin Zhu; Dr. Lili Lin; Prof. Dr. Xiaoming Feng


Book ID
101838188
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
325 KB
Volume
17
Category
Article
ISSN
0947-6539

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Highly Enantioselective Direct Michael A
✍ Jing Wang; Wentao Wang; Xiaohua Liu; Zongrui Hou; Lili Lin; Xiaoming Feng 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 396 KB

## Abstract The __N__,__N′__‐dioxide–Sc(OTf)~3~ complex was applied in the asymmetric Michael reaction of 1__H__‐benzotriazole with chalcones to give the corresponding N‐1 products in excellent yields (up to 99 %) with excellent enantioselectivities (up to 99 % __ee__). Further transformation into