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Enantioselective Bromoaminocyclization of Allyl N -Tosylcarbamates Catalyzed by a Chiral Phosphine–Sc(OTf) 3 Complex

✍ Scribed by Huang, Deshun; Liu, Xiaoqin; Li, Lijun; Cai, Yudong; Liu, Weigang; Shi, Yian


Book ID
120300755
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
770 KB
Volume
135
Category
Article
ISSN
0002-7863

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Highly Enantioselective Direct Michael A
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## Abstract The __N__,__N′__‐dioxide–Sc(OTf)~3~ complex was applied in the asymmetric Michael reaction of 1__H__‐benzotriazole with chalcones to give the corresponding N‐1 products in excellent yields (up to 99 %) with excellent enantioselectivities (up to 99 % __ee__). Further transformation into