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Asymmetric Synthesis of Chiral Heterocyclic Amino Acids via the Alkylation of the Ni(II) Complex of Glycine and Alkyl Halides

โœ Scribed by Chen, Hui; Wang, Jiang; Zhou, Shengbin; Liu, Hong


Book ID
127178539
Publisher
American Chemical Society
Year
2014
Tongue
English
Weight
767 KB
Volume
79
Category
Article
ISSN
0022-3263

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Double asymmetric synthesis: Palladium c
โœ J.P. Genet; N. Kopola; S. Juge; J. Ruiz-Montes; O.A.C. Antunes; S. Tanier ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 270 KB

A new double asymmetric induction in carbon-carbon bond formation is -achieved by the use of palladium chiral complexes in the alkylation of chiral Schiff bases1 derived from glycine. High diastereoisomeric excesses are obtained (90-999) using N.N-cyclohexylsulfamoylisobornyl derivatives and DIOP as