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Asymmetric Synthesis of (−)-Brevipolide H through Cyclopropanation of the α,β-Unsaturated Ketone

✍ Scribed by Lin, Jing-Wen; Kurniawan, Yudhi Dwi; Chang, Wen-Jung; Leu, Wohn-Jenn; Chan, She-Hung; Hou, Duen-Ren


Book ID
126517294
Publisher
American Chemical Society
Year
2014
Tongue
English
Weight
663 KB
Volume
16
Category
Article
ISSN
1523-7060

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Synthesis of chiral β -alkoxy- α,β -unsa
✍ André Lubineau; Annie Malleron 📂 Article 📅 1984 🏛 Elsevier Science 🌐 French ⚖ 153 KB

The title compounds are synthesized in one-pot from the easily available sodium salts of unsymmetrical 1,3\_dicarbonyl derivatives and chiral alkoxides. Die&.-Alder additions still play a major role in preparative organic chemistry and asymmetric induction in such reactions represents a challenge i