Asymmetric Synthesis of an Isoxazolidine Nucleoside Analogue of Thymine Polyoxin C. -The first total synthesis of the isoxazolidine amino acid nucleoside analogue (VI) is based on the stereoselective nucleophilic addition of the silyl ketene acetal (II) to the enantiopure N-benzyl nitrone (I) as th
Asymmetric synthesis of an isoxazolidine nucleoside analog of thymine polyoxin C
β Scribed by Pedro Merino; Santiago Franco; Francisco L. Merchan; Tomas Tejero
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 230 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
A new strategy for assembly of glycosyl a-aminoacids via the stereocontrolled buildup of a serine-derived penaldic acid equivalent (i.e. I + II) is illustrated by the asymmetric synthesis of thymine polyoxin C.
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