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Asymmetric Synthesis of .alpha.-Aminophosphonates via Diastereoselective Addition of Lithium Diethyl Phosphite to Chelating Imines

✍ Scribed by Yager, Kraig M.; Taylor, Carol M.; Smith, Amos B.


Book ID
115467133
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
261 KB
Volume
116
Category
Article
ISSN
0002-7863

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## Abstract An efficient methodology for the synthesis of α‐aminophosphonates has been developed taking advantage of the __tert__‐butyldimethylsilyl triflate activated addition of diethyl phosphite to __N__‐benzyl nitrones derived from chiral α‐alkoxy and α‐(Boc‐amino) aldehydes. The stereoselectiv