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Asymmetric synthesis of a phosphorus analog of naturall-carnitine

โœ Scribed by V. V. Nesterov; O. I. Kolodyazhnyi


Book ID
111459023
Publisher
Springer
Year
2006
Tongue
English
Weight
30 KB
Volume
76
Category
Article
ISSN
1070-3632

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A practical asymmetric synthesis of carn
โœ M. Kitamura; T. Ohkuma; H. Takaya; R. Noyori ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 175 KB

The first efficient chemical synthesis of (I?)-carnitine has been accomplished on the basis of homogeneous enantioselective hydrogenation of ethyl 4-chloro-3oxobutanoate. We recently demonstrated that the BINAP-based Ru(I1) catalysts have remarkable