Asymmetric synthesis of 3β-acetoxy-17, 17-ethylendioxy-15β, 16β-methylene-5-androsten-7β-ol
✍ Scribed by Liu, Feng-liang ;Zhou, Kang-gen ;Yang, Wei-jun ;Yang, Xi-yun
- Book ID
- 107506106
- Publisher
- Chinese Electronic Periodical Services
- Year
- 2004
- Tongue
- English
- Weight
- 313 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1005-9784
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📜 SIMILAR VOLUMES
In the crystal structure of the title compound, C 22 H 30 O 4 , rings A and C have slightly distorted chair conformations, ring B shows an approximate symmetric half-chair conformation and ring D is in an envelope conformation. The molecules are connected by weak intermolecular C-HÁ Á ÁO hydrogen bo
In the title molecule, C 22 H 29 ClO 4 , all bond lengths and angles show normal values. Rings A and C have slightly distorted chair conformations, while rings B and D show envelope conformations. Weak intermolecular C-HÁ Á ÁO hydrogen bonds link the molecules into chains running along the b axis.
## Abstract A method has been described for the synthesis of tritiated [7‐^3^H]‐3β,16β‐dihydroxy‐5‐androsten‐17‐one of high specific activity starting from [7‐^3^H]‐5‐androsten‐17‐one. The identity of the radioactive steroid was established by thin layer chromato‐graphy, gas chromatography and gas