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Asymmetric synthesis of 3′,4′-Di-O-(−)-camphanoyl-(+)-Cis-khellactone (DCK), a potent anti-HIV agent

✍ Scribed by Lan Xie; Michael T Crimmins; Kuo-Hsiung Lee


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
241 KB
Volume
36
Category
Article
ISSN
0040-4039

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ChemInform Abstract: Anti-Aids Agents. P
✍ L. XIE; Y. TAKEUCHI; L. M. COSENTINO; K.-H. LEE 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 2 views

Anti-Aids Agents. Part 33. Synthesis and anti-HIV Activity of Mono-Methyl Substituted 3',4'-Di-O-(-)-camphanoyl-(+)-cis-khellactone (DCK) Analogues. -The title compounds (VII) are synthesized using a Claisen rearrangement and a Sharpless dihydroxylation reaction as key steps. The methyl derivatives