Approaches to 2-substituted chroman-4-on
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Kevin J Hodgetts
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Article
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2001
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Elsevier Science
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French
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Two approaches to optically active 2-substituted chroman-4-ones are described. The first utilized the oxidation of a preformed chroman ring and the second an intramolecular Mitsunobu cyclization. The methodology was applied to the synthesis of the biologically active natural product (-)-pinostrobin