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Asymmetric Synthesis of 2-Amino-3-hydroxynorbornene-2-carboxylic Acid Derivatives

✍ Scribed by Abbiati, Giorgio; Clerici, Francesca; Gelmi, Maria Luisa; Gambini, Andrea; Pilati, Tullio

Book ID
127389298
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
85 KB
Volume
66
Category
Article
ISSN
0022-3263

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A new route towards the asymmetric preparation of quaternary 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives has been developed. The key step involves an intramolecular Pictet-Spengler reaction of an oxazolidino ester.