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Asymmetric synthesis of 2-amino-1,4-diols

✍ Scribed by Ben L. Feringa; B. de Lange


Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
247 KB
Volume
29
Category
Article
ISSN
0040-4039

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Asymmetric synthesis of 4-amino-3,4-dihy
✍ Andreas Burgard; Hans-Jochen Lang; Uwe Gerlach πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 385 KB

Highly enantioselective reduction of 3,4-dihydro-2,2-dimethyl-2H-l-benzopyran-4-ones 3 s-e by BH3 was achieved in the presence of catalytic amounts of Corey's oxazaborolidine 4 to afford the corresponding 3,4-dihydro-2,2dimetbyl-2H-l-~nzopyran-4-ols 2a-e in quantitative yields. These benzopyran-4-ol