Asymmetric Synthesis of 1,4-Disubstituted Tetrahydroioquinolines
β Scribed by Valerie Jullian; Jean-Charles Quirion; Henri-Philippe Husson
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 261 KB
- Volume
- 2000
- Category
- Article
- ISSN
- 1434-193X
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## Abstract **A breakthrough** in the asymmetric hydroboration of notoriously difficult 1,1βdisubstituted alkenes using a new family of highly effective hydroboration reagents is described (see scheme). The intermediate boranes can be oxidized to alcohols or used in SuzukiβMiyaura crossβcoupling re
Compound (5) crystallizes from n-hexane in the space group C:h-P21/~ with u= 1717.0(8), b=775.2(4), c = 1876.0(8) pm, p= 117 57(3)", Z = 4 . 3253 independent non-7ero reflection< were recorded with an automatic single crystal diffrdctometer (Siemenh) with Mok,. radiation (4 36 .-2 0 5 57.94