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ASYMMETRIC SYNTHESIS OF 1-AMINOALKYLPHOSPHONIC ACIDS

✍ Scribed by Jacquier, Robert; Lhassani, Mohamed; Petrus, Clement; Petrus, Francoise


Book ID
115472971
Publisher
Taylor and Francis Group
Year
1993
Tongue
English
Weight
313 KB
Volume
81
Category
Article
ISSN
1042-6507

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Optically active 1-aminoalkylphosphonic acid derivatives were synthesized in moderate yields and optical purities via Mannich-type reactions of benzyl carbamate, aldehydes, and optically pure chlorophosphites. Side chain-functionalized depsiphosphonopeptides were also prepared in satisfactory yields