Mit weniger als 1 Molโ% eines chiralen VanadiumโKatalysators und wรครrigem H~2~O~2~ als Oxidationsmittel kรถnnen unter einfachsten Reaktionsbedingungen Sulfide zu optisch aktiven Sulfoxiden (mit bis zu 85% __ee__) umgesetzt werden [Gl. (a)]. R, Rโฒ ๏ฃพ Alkyl, Aryl .magnified image
โฆ LIBER โฆ
Asymmetric Sulfide Oxidation with Vanadium Catalysts and H2O2
โ Scribed by Prof. Dr. Carsten Bolm; Dipl.-Chem. Frank Bienewald
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 385 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0044-8249
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## Abstract For Abstract see ChemInform Abstract in Full Text.
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Sulfoxidation catalysts generated in situ from titanium(IV) isopropoxide and enantiopure Schiff bases promote the enantioselective oxidation of alkyl aryl sulfides to the corresponding sulfoxides at low catalyst loadings (<1 mol%), 30% aqueous hydrogen peroxide being the terminal oxidant. Upon scree