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Asymmetric reduction of α-keto esters with thermophilic actinomycete: purification and characterization of α-keto ester reductase from Streptomyces thermocyaneoviolaceus IFO 14271

✍ Scribed by Kohji Ishihara; Hitomi Yamaguchi; Hiroki Hamada; Kaoru Nakamura; Nobuyoshi Nakajima

Book ID: 114396541
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 358 KB
Volume: 10
Category: Article
ISSN: 1381-1177
DOI: 10.1016/s1381-1177(99)00114-9

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## Abstract The enantioselective synthesis of methyl (__R__)‐mandelate and methyl (__R__)‐__o__‐chloromandelate was investigated using an NADH‐dependent carbonyl reductase from __Thermus thermophilus__ (TtADH) and, separately, archaeal glucose dehydrogenase and __Bacillus stearothermophilus__ alcoh