## Abstract For Abstract see ChemInform Abstract in Full Text.
Asymmetric oxidation of racemic 2-substituted 1,3-oxathianes
β Scribed by Bunnai Saito; Tsutomu Katsuki
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 101 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0899-0042
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π SIMILAR VOLUMES
2-(Alkylthio)-2-benzylthiolane 1-oxides (1a, b) and 2-esters (Ξ΄-sultines) 2 are formed. Only (1R\*,2S\*)-1b is reactive whereas (1R\*,2R\*)-1b is not attacked. This observation is (alkylthio)-2-(Ξ±-hydroxybenzyl)thiolane 1-oxides (1c, d) are oxidized with [bis(trifluoroacetoxy)iodo]benzene (PIFA). ex
Stereochemically Controlled Synthesis of Substituted 1,2-Oxathianes. -Treatment of 4-sulfanyl-1,3-diols containing a tertiary SH group with tosyl chloride and triethylamine results in high-yielding cyclization to give 1,2-oxathianes as single diastereomers. Subjecting the sulfanyldiol (IX) to analo