Asymmetric Michael addition of ketones to nitroolefins: pyrrolidinyl-oxazole-carboxamides as new efficient organocatalysts
β Scribed by Kamal, Ahmed; Sathish, Manda; Srinivasulu, Vunnam; Chetna, Jadala; Chandra Shekar, Kunta; Nekkanti, Shalini; Tangella, Yellaiah; Shankaraiah, Nagula
- Book ID
- 126507141
- Publisher
- Royal Society of Chemistry
- Year
- 2014
- Tongue
- English
- Weight
- 881 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1477-0520
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## Abstract A highly diastereoselective and enantioselective Michael addition of cyclohexanone, acetone and other ketones to nitroolefins was developed by the use of an amine organocatalyst based on bispidine. Additionally, a theoretical study of transition structures revealed that this bispidineβb
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