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Asymmetric Mannich Synthesis of β-Amino Acids with Two New Stereogenic Centers at the α and β Positions

✍ Scribed by Prof. Dr. Horst Kunz; Dr. Andreas Burgard; Dr. Dirk Schanzenbach


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
265 KB
Volume
36
Category
Article
ISSN
0044-8249

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α,β-Dehydro-amino acid residues in the d
✍ Pushkar Sharma; Punit Narula; Tej P. Singh 📂 Article 📅 1994 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 470 KB

The dehydro-residue containing peptides N-Ac-dehydro-Phe-L-Leu-OCH3 ( I ) and N-Acdehydro-Phe-NorVal-OCH, (11) were synthesized by the usual workup procedures. The peptides crystallize from their solutions in methanol in space group P6,: ( I ) a = b = 12.528(2) A, c = 21.653(5) A; (11) a = b = 12.53