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✦ LIBER ✦
Asymmetric Intermolecular Pauson−Khand Reaction of Symmetrically Substituted Alkynes
✍ Scribed by Ji, Yining; Riera, Antoni; Verdaguer, Xavier
- Book ID
- 111943173
- Publisher
- American Chemical Society
- Year
- 2009
- Tongue
- English
- Weight
- 536 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1523-7060
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The first practical asyuumtic vemon of the intamolecuhr Pausoa-Khpnb reaction has been developed baxl on novel &id (non-tic) alkoxy acetyleale dkwbalt tuaxbalyl mmplexe& The major addti km ( 1R 2S)-2-pl~eoylcyclohexyloxyethyne and nohmadim, isolated in 58% yield, is shown to be useful for obtaining
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## Abstract The reaction proceeds strictly regioselectively: the fluorinated substituent is always found at the α‐position to the enone.
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